Role of Platelet Concentrates in Periodontal Regeneration- An Overview

Abstract

Platelet plays an important role in hemostasis and wound healing; platelet growth factors are well known for healing cytokines. Platelet concentrate is derived from the patient’s own blood, this technique uses a centrifuge to separate out the patient’s own blood components by their densities, RBC are denser that will move to the bottom, plasma fraction is least dense will float on the top layer, the (buffy coat) which contain majority of platelet will be sandwiched between the plasma and above RBC. Platelet Rich Plasma (PRP) and Platelet Rich Fibrin (PRF) are extensively used analogue platelet concentrate in periodontal regeneration. PRF has better efficiency when compare to PRP. This rationale has been attributed to the difference in structure of fibrin matrix. The Concentrated Growth Factor (CGF) is an excellent and a novel regenerative tool in the field of periodontics and regenerative dentistry. It is adopted without the use of chemical which is more ecofriendly. It consists of numerous growth factors which enhance its action and promotes wound healing. It is used along with the autologous bone particle to induce bone regeneration. It has the ability to regenerates both soft and hard tissues. It is effective, economical, bio compactible, resorbable biomaterial.