Review on Effect of Binders on Nimesulide Tablets

Abstract

Binders are used in tablet formulations to enhance flexibility and hence increase inter particulate bonding strength. The research and development of new excipients are used as binding agents in tablet formulation. This is due to the fact that different binding agents can be used to achieve varying tablet mechanical strengths and drug release qualities for distinct medicinal purposes. Binders are substances that help the granules stick together. The creation of granules of derived hardness and size guarantees the tablet remains intact following compression while also increasing the flow characteristics. The aim of the review is to focus on the effect of the binders like starch, sucrose, tracaganth; hydroxy propyl methyl cellulose, carboxy methyl cellulose, and gelatin possess binding capacity in Nimesulide tablets.