ICP-OES Analysis of Siddha Formulation Gandhi Mezhugu

Abstract

Background: The Gandhi Mezhugu (GM) is a herbomineral formulation used for treating all types of skin diseases. Objective: The objective of the present study is to detect heavy metals (arsenic, lead, cadmium, mercury) and other elements within the permissible limits as per WHO guidelines present in the Siddha herbomineral Formulation “Gandhi Mezhugu”. Materials and Methods: The ingredients were collected and purified and the drug was prepared as per Siddha literature “The Siddha Formulary of India (Tamil) part-1”. Here, the drug was subjected to standardization by simultaneous ICP-OES analysis equipment (PERKIN ELMER OPTIMA 5300 DV). Result: This paper revealed the therapeutic safer level of heavy metals and other elements present in Gandhi Mezhugu, as per WHO guidelines with the help of simultaneous ICP- OES analysis equipment (PERKIN ELMER OPTIMA 5300 DV). Conclusion: From the ICP-OES analysis reveals that Gandhi mezhugu are free from toxicity there by proving the safety of its utilization in siddha system. This study forms the base for the pharmaceutical analysis of Gandhi Mezhugu (GM) which will be followed by safe and efficacy studies later.