Histopathology as a Tool for Assessing the Extent of Toxicity of Quinalphos in Fish

Abstract

Study was conducted to assess the histopathological damage induced by the organophosphate pesticide quinalphos on liver and brain in Anabas testudineus and Oreochromis mossambicus. In this study the fishes were exposed to a sub lethal concentration of pesticide for 30 days and examine the damage induced by the pesticide. Due to the effect of pesticide, changes occurs in the liver and brain of fishes. In liver, loss of normal architecture of parenchyma and hepatic cells were observed. Degeneration of neurons and dorsal and ventral olfactory area, blood streaks, vacuolation were observed in brain. Lesions in the liver leads to delayed function and also affect the central nervous system as a result of brain damage. This happens due to the neurotoxicity of pesticides. Which alters the physiology and normal health of fish. Increasing duration of exposure leads to, histopathological damage become more severe.