Effects of Oxidative Stress and Some Risk Factors Associated with Male Infertile Subjects in Jigawa, Nigeria
Keywords:
Male infertility, Oxidative stress, Risk-factors, SemenAbstract
Male factor infertility is one of the discussed health issues globally in recent times. It accounts for about 20%-30% of infertility cases. A lot of factors involved significantly affect semen quality thereby contributing to male infertility. One hundred and twenty-six (126) participants were recruited in this study; 81 infertile and 45 control subjects. Socio-demographic characteristics of the participants were collected through interviewer administered questionnaire. Seminal fluid collected was analyzed using a computer-aided sperm analysis system. Serum sex hormone, 8-iso-PGF2α and antioxidant vitamins were accordingly determined using Elisa and colorimetric enzymatic techniques. Results obtained were compared among the groups. Significantly decreased levels of all antioxidant vitamins were observed among infertile subjects compared to controls. Results showed no significant change in FSH levels between the variables but elevated LH and a reduced testosterone values was observed among infertile. Furthermore, poor semen quality and elevated 8-iso-PGF2α was observed among infertile in comparison with control group. In conclusion, male infertility is a multi-factorial with smoking, alcohol consumption, oxidative stress, obesity and decreased vitamins playing a greater role in the course.
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Copyright (c) 2023 Yamuna Aminu Kani, Yahaya Muhammad, Abdullahi Abba Habib, Abdulrahman Abubakar Tahir, Abdullahi Muhammad Kabir, Badamasi Musa, Sani Iliya, Mahmud Inusa Yandutse, Rehinatu Nasir Adejuo, Muhammad Adamu Ibrahim
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This work is licensed under a Creative Commons Attribution 4.0 International License.